• Ешқандай Нәтиже Табылған Жоқ

The Gel/OxAlg mixes with a low concentration of 1:1 can be utilized as inks to generate hydrogel scaffolds for 3D printing. By merging single-step cryogenic synthesis and 3D printing technology, it is feasible to create low-cost scaffolds with high accuracy and pore morphology of super-hundred-microns. Nonetheless, as cryo synthesis necessitates exposure to extremely cold temperatures, producing cell-filled scaffolds in a single step, as recommended by bioprinting, is not achievable. Nevertheless, the scaffolds that are generated display a distinctive shape and biocompatibility, making them promising for various tissue regeneration purposes.

Scaffolds with a PA higher than 75% can be effectively produced through 3D printing using a blend of Gel/OxAlg at a concentration of 2.86% w/v (1:1). These scaffolds have exceptional swelling ability and can expand up to 1800% of their initial dry weight, which supports cell migration. Additionally, they provide sufficient mechanical support for temporary usage and tissue volume preservation. The scaffolds maintained over 85% of their initial mass and had good elasticity, with a value of about 0.15 kPa, after being exposed to aqueous conditions for three weeks. The 2.86% w/v (1:1) Gel/OxAlg scaffold has highly attractive structural features, long-lasting mechanical stability and integrity, good biocompatibility, and a unique extra-large porous morphology, making it ideal for use in tissue engineering applications.



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