Основываясь на опыте ближневосточного респираторного синдрома и недавних данных [20, 33], наличие плеврального выпота может указывать на неблагоприятный прогноз при COVID-19. Некоторые исследователи предполагают, что наличие фиброза свидетельствует о хорошем прогнозе для пациента с COVID-19 при стабилизации статуса заболевания [27].
Radiological findings in 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study // Lancet Infect Dis. Diagnosis of COVID-19 for pandemic management: a state-of-the-art review // Biosens Bioelectron.
COVID-19 ПАНДЕМИЯСЫ ЖАҒДАЙЫНДА ПНЕВМОНИЯМЕН АУЫРАТЫН НАУҚАСТАРДА РЕСПИРАТОРЛЫҚ ҚОЛДАУ ЕРЕКШЕЛІКТЕРІ
FEATURES OF RESPIRATORY SUPPORT FOR PATIENTS WITH PNEUMONIA IN THE CONTEXT OF THE COVID-19 PANDEMIC
Objective – analysis of articles on respiratory support for coronavirus infection COVID-19 published in the most authoritative evidence-based sources. Results: The main task in the treatment of acute respiratory failure is adequate oxygenation, as hypoxia can lead to severe and irreversible functional disorders.
ОСОБЕННОСТИ РЕСПИРАТОРНОЙ ПОДДЕРЖКИ ПАЦИЕНТОВ С ПНЕВМОНИЕЙ В УСЛОВИЯХ ПАНДЕМИИ COVID-19
ANALYSIS OF AWARENESS OF HEALTHCARE PROFESSIONALS ABOUT PAIN SYNDROME MANAGEMENT IN PROVIDING PALLIATIVE
АНАЛИЗ ОСВЕДОМЛЕННОСТИ МЕДИЦИНСКИХ РАБОТНИКОВ ОБ УПРАВЛЕНИИ БОЛЕВЫМ СИНДРОМОМ ПРИ ОКАЗАНИИ
Проведено поперечное исследование путем опроса медицинских работников города Алматы Республики Казахстан с 1 марта 2021 года по 30 сентября 2021 года.
ҚАЗАҚСТАН РЕСПУБЛИКАСЫНДА ОНКОЛОГИЯЛЫҚ НАУҚАСТАРҒА ПАЛЛИАТИВТІК КӨМЕК КӨРСЕТУ КЕЗІНДЕГІ АУЫРСЫНУДЫ
БОЛУЫН ТАЛДАУ
In this study, we conducted an analysis of health care staff's awareness of pain management in the provision of palliative care to cancer patients in Kazakhstan in the study population and found that 36.84% of respondents had no experience of pain relief in a patient with concurrent chronic pain syndrome. Analysis of the patient-related barriers in cancer pain management in Turkish patients // J Pain Symptom Manage.
GEOSPATIAL ANALYSIS OF TERRITORIAL ASSESIBILITY OF THE AMBULANCE EMERGENCY STATION COVERAGE
OF THE WITH ACUTE CORONARY SYNDROME INCIDENTS IN PAVLODAR (KAZAKHSTAN)
ПРОСТРАНСТВЕННЫЙ АНАЛИЗ ТЕРРИТОРИАЛЬНОЙ ДОСТУПНОСТИ СТАНЦИИ СКОРОЙ МЕДИЦИНКОЙ ПОМОЩИ ПРИ ОСТРОМ
ПАВЛОДАР ҚАЛАСЫ (ҚАЗАҚСТАН) БОЙЫНША ЖЕДЕЛ КОРОНАРЛЫҚ СИНДРОМЫ КЕЗІНДЕГІ ЖЕДЕЛ КӨМЕК КӨРСЕТУ СТАНЦИЯСЫНЫҢ
AND 17A: THE RELATIONSHIP OF GENE POLYMORPHISMS TO DISEASE AND CYTOKINE LEVELS IN
In the case-control study, there were 89 patients and 422 healthy individuals from the Kazakh population. Thus, IL17A gene polymorphisms can be associated with brucellosis disease, with the level of the cytokine itself in the Kazakh population.
Актуальность: When predicting the clinical course of brucellosis, the participation of a genetic factor, in particular gene polymorphism of some cytokines, which are essential in the development of the disease, is not excluded. The aim of the study was to study the associations of the polymorphisms of the IL10 and IL17 genes with brucellosis, as well as their relationship to the production of the same cytokines in brucellosis patients of Kazakh nationality.
10 ЖӘНЕ 17А ИНТЕРЛЕЙКИНДЕРІ: ҚАЗАҚ ПОПУЛЯЦИЯСЫНДА ГЕН ПОЛИМОРФИЗМДЕРІНІҢ БРУЦЕЛЛЕЗ АУРУЫМЕН
Conflicting results were obtained by studying the polymorphism rs2275913 of the IL-17A gene in patients with tuberculosis. In patients with brucellosis of the GA genotype, hyperproduction of IL-17A was observed in comparison with the control group.
МИКРОБИОЛОГИЧЕСКИЕ ПОКАЗАТЕЛИ НЕОСЛОЖНЕННЫХ УРОИНФЕКЦИЙ У АМБУЛАТОРНЫХ БОЛЬНЫХ
MICROBIOLOGICAL INDICATORS OF OUTPATIENTS’
Results: During the study period, 158 clinical samples were included, 75 strains were isolated; of them and the most isolated microorganisms was E.coli - 76%. Conclusion: Based on our results, the most common causative agent of uncomplicated urinary tract infection in outpatients was E.coli with a high degree of susceptibility to nitrofurantoin 94.7% and co-trimoxazole 89.4%.
АМБУЛАТОРИЯЛЫҚ ПАЦИЕНТЕРІНІҢ АСҚЫНБАҒАН УРОЛОГИЯЛЫҚ ИНФЕКЦИЯЛАРДЫҢ МИКРОБИОЛОГИЯЛЫҚ
Микробный пейзаж мочи амбулаторных пациентов
Антибиотикочувствительность штаммов E.coli, выделенных от амбулаторных пациентов с ИМП
Микробный пейзаж мочи стационарных пациентов отделения урологии
Antibiotic susceptibility of bacterial strains isolated from patients with community-acquired urinary tract infections in France. Community-acquired urinary tract infection by Escherichia coli in the era of antibiotic resistance // BioMed Research International.
ҚАУІП ФАКТОРЛАРЫНЫҢ ӘСЕРІНЕН ЖҮРЕК - ҚАНТАМЫР ЖҮЙЕСІ АУРУЛАРЫ БОЙЫНША МҮГЕДЕКТІК ДЕҢГЕЙІН АРТТЫРУ
ROLE OF FORECAST TABLE IN DETERMINING THE POSSIBILITY OF INCREASING THE DISABILITY LEVEL FOR CARDIOVASCULAR
Objective: The main objective of the study is to create a scientific basis for preventive measures aimed at preventing functional impairment caused by diseases of the cardiovascular system. The use of the method of differential medical examination increased the activity of preventive work among diseases of the cardiovascular system, contributed to a comfortable organization of life and living conditions for patients, promoted a healthy lifestyle and contributed to improving the quality of work in home hospitals, nurses and social workers.
РОЛЬ ПРОГНОЗНОЙ ТАБЛИЦЫ В ОПРЕДЕЛЕНИИ ВОЗМОЖНОСТИ ПОВЫШЕНИЯ УРОВНЯ ИНВАЛИДНОСТИ
Әлеуметтік себептер
- Әлеуметтік-гигиеналық себептер 2.1 Селитебтік атмосфералық ауаның
- Әлеуметтік-психологиялық себептер
- Медициналық-биологиялық себептер
ЖҚАЖА арасында жүргізілетін дифференциалдық профилактика жүйесі мен медициналық - әлеуметтік көмек моделі
Doklad po statistike serdechno-sosudistykh zabolevanii v 34 stranakh mira dlya Vsemirnoi organizatsii zdravookhraneniia [Verslag oor kardiovaskulêre siektestatistieke in 34 lande vir die Wêreldgesondheidsorganisasie]. Lechenie i profilaktika arterialnoi gipertenzii v usloviyakh promyshlennogo predpriyatiya [Behandeling en voorkoming van arteriële hipertensie in 'n industriële onderneming].
INFORMING THE PATIENT ABOUT OF IMPLANTABLE CARDIOVERTER DEFIBRILLATORS IN KAZAKHSTAN
ИНФОРМИРОВАНИЕ ПАЦИЕНТОВ ОБ ИМПЛАНТИРУЕМЫХ КАРДИОВЕРТЕРАХ-ДЕФИБРИЛЛЯТОРАХ В КАЗАХСТАНЕ
ҚАЗАҚСТАНДА ИМПЛАНТТЫ КАРДИОВЕРТЕР-
Information about how the OCD works is little or completely unsatisfied with 13.4% of female respondents P <0.073. The information received about the benefits of ICD was noted neutrally by 6.3% of men, and little or completely dissatisfied by 26.7% of women (P <0.003). Informing the participants about the shortcomings of the ICD, 6.3% of men and 26.7% of women, P <0.019, indicated neutral or worse, not sufficiently satisfactory.
АНАЛИЗ СМЕРТНОСТИ ОТ НЕСЧАСТНЫХ СЛУЧАЕВ, ТРАВМ И ОТРАВЛЕНИЙ В РЕСПУБЛИКЕ КАЗАХСТАН
ANALYSIS OF MORTALITY FROM ACCIDENTS, INJURIES AND POISONING IN THE REPUBLIC OF KAZAKHSTAN
The purpose: is to study deaths from accidents, injuries and poisoning in the Republic of Kazakhstan. A comparative retrospective analysis of deaths due to accidents, injuries and poisoning in the context of the regions of the Republic of Kazakhstan for 2010-2020 was carried out according to the statistical collections. Over the past 10 years, a significant decrease in deaths due to accidents, injuries and poisoning has been observed in the dynamics of the Republic of Kazakhstan.
ҚАЗАҚСТАН РЕСПУБЛИКАСЫНДА ЖАЗАТАЙЫМ ОҚИҒАЛАРДАН, ЖАРАҚАТТАРДАН ЖӘНЕ УЛАНУДАН БОЛАТЫН
The rate of deaths from accidents, injuries and poisoning in the context of the regions of the Republic of Kazakhstan for 2019 (per 100 thousand inhabitants)). 419 "On approval of the action plan for ensuring safe work in the Republic of Kazakhstan until 2025"]. 1113 For the approval of the State Health Development Program of the Republic of Kazakhstan "Salamatty Kazakstan.
KAZAKHSTAN MODEL OF HEALTHCARE FINANCING THROUGH PUBLIC HEALTH PRINCIPLE: EXPERIENCE AND PROSPECTS
КАЗАХСТАНСКАЯ МОДЕЛЬ ФИНАНСИРОВАНИЯ ЗДРАВООХРАНЕНИЯ ПО ПРИНЦИПУ ОБЩЕСТВЕННОГО
ҚОҒАМДЫҚ ДЕНСАУЛЫҚ САҚТАУ ҚАҒИДАТЫ БОЙЫНША ДЕНСАУЛЫҚ САҚТАУДЫ ҚАРЖЫЛАНДЫРУДЫҢ ҚАЗАҚСТАНДЫҚ
ФАКТОРЫ, СПОСОБСТВУЮЩИЕ ВНЕДРЕНИЮ МЕТОДА КЕНГУРУ В ПРАКТИКУ ПЕРИНАТАЛЬНЫХ ЦЕНТРОВ РЕСПУБЛИКИ КАЗАХСТАН
FACTORS CONTRIBUTING TO THE INTRODUCTION OF THE KANGAROO METHOD INTO THE PRACTICE OF PERINATAL CENTERS
ҚАЗАҚСТАН РЕСПУБЛИКАСЫНЫҢ ПЕРИНАТАЛДЫҚ
ОРТАЛЫҚТАРЫНЫҢ ТӘЖІРИБЕСІНЕ КЕНГУРУ ӘДІСІН ЕНГІЗУГЕ ЫҚПАЛ ЕТЕТІН ФАКТОРЛАР ЖӘНЕ КЕДЕРГІЛЕР
ОПЫТ ЗАРУБЕЖНЫХ СТРАН В ПРОВЕДЕНИИ МЕРОПРИЯТИЙ ПО ПРОФИЛАКТИКЕ БОЛЕЗНЕЙ СИСТЕМЫ КРОВООБРАЩЕНИЯ
ОБЗОР ЛИТЕРАТУРЫ
THE EXPERIENCE OF FOREIGN COUNTRIES IN CARRYING OUT MEASURES FOR THE PREVENTION OF DISEASES
Out of 50, only 10 of the most effective CVD prevention programs were selected for subsequent analysis according to the results of several studies conducted during this period. For the subsequent analysis, programs from 10 countries were selected that managed to reduce mortality from cardiovascular diseases by more than 50%. Health departments, local health committees, voluntary organizations and community volunteers played a role in the implementation of the program and interventions were carried out in a variety of settings, including workplaces and schools.
ҚАН АЙНАЛЫМЫ ЖҮЙЕСІ АУРУЛАРЫНЫҢ АЛДЫН АЛУ ЖӨНІНДЕГІ ІС-ШАРАЛАРДЫ ЖҮРГІЗУДЕГІ ХАЛҚАРАЛЫҚ
The literature search was carried out in the PubMed, Google Scholar, Medline, Cyberleninka and eLibrary databases, using key words (circulatory diseases, prevention, preventive measures) from 1970 to 2020, since during this period many foreign countries managed to reduce mortality due to CVD. Thus, almost all countries' programs included a media approach, using a combination of radio, television and print materials to deliver heart health messages. It follows from the above that 10 countries managed to reduce CVD mortality by 50%.
ЕЛДЕРДІҢ ТӘЖІРИБЕСІ. ӘДЕБИЕТКЕ ШОЛУ
Страны, которым удалось снизить показатели смертности от ССЗ (%) [29,39]
- mail: [email protected] Тел.: 87471944906
Community-based primary prevention of cardiovascular disease in Switzerland: methods and results from the national research program (NRP 1A). Community education for cardiovascular disease prevention: changes in risk factors in the Minnesota Heart Health Program // American journal of public health. The long-term effects of a cardiovascular disease prevention trial: the Stanford Five-City Project // American journal of public health.
РОЛЬ ХОЛТЕРОВСКОГО МОНИТОРИРОВАНИЯ ЭКГ В ДИАГНОСТИКЕ ФЕНОМЕНА ИШЕМИЧЕСКОГО ПРЕКОНДИЦИОНИРОВАНИЯ
ОБЗОР ЛИТЕРАТУРЫ Асель А. Чиныбаева
THE ROLE OF HOLTER ECG MONITORING IN THE DIAGNOSIS OF THE PHENOMENON OF ISCHEMIC PRECONDITIONING AND
The time dependence of the occurrence of IP has been shown in experimental and clinical studies as protection of the myocardium from IP. Currently, Holter monitoring is used not only to clarify the diagnosis of coronary heart disease, but also to control the treatment of patients with coronary artery disease, which allows you to get objective information about how many episodes of myocardial ischemia they have in the normal life of the patient. decreased under the influence of the prescribed therapy. The presence of the phenomenon of adaptive protection significantly affects the level of coronary reserve and is characterized by a reduction in the duration of ischemic episodes, the total index of ischemia and an increase in exercise tolerance.
ИШЕМИЯЛЫҚ АЛДЫН АЛА КОНДИЦИЯЛАУ ФЕНОМЕНІН
Results: HM makes it possible to identify episodes of ischemia, either caused by an increase in myocardial oxygen demand with an increase in heart rate, or dependent on a violation of coronary circulation without an increase in heart rate, or both at the same time . To evaluate the dynamics of the disease, usually not only the characteristics of individual episodes of ischemia (number, duration, severity of ECG changes) are used, but also integral indicators, the most commonly used of which is the "total duration of ischemia per day", which is the sum of the duration of all episodes. Multi-day HM offers the possibility of effective selection of anti-anginal therapy in patients with stable angina pectoris with the PV phenomenon.
ДИАГНОСТИКАЛАУДА ЖӘНЕ АНТИАНГИНАЛЬДІ ЕМНІҢ ТИІМДІЛІГІН БАҒАЛАУДА ЭКГ ХОЛТЕР МОНИТОРЛАУЫНЫҢ РӨЛІ. ӘДЕБИ ШОЛУ
ВОЗМОЖНОСТИ ХОЛТЕРОВСКОГО МОНИТОРИРОВАНИЯ ЭКГ У ПАЦИЕНТОВ С ОСТРЫМ КОРОНАРНЫМ СИНДРОМОМ
POSSIBILITIES OF HOLTER ECG MONITORING IN PATIENTS WITH LOW-RISK ACUTE CORONARY SYNDROME
ҚАУІПТІЛІГІ ТӨМЕН ЖІТІ ЖЕДЕЛ КОРОНАРЛЫҚ СИНДРОМЫ БАР ПАЦИЕНТТЕРДЕ ХОЛТЕРЛІК ЭКГ МОНИТОРЛАУ МҮМКІНДІКТЕРІ
Алгоритм поиска и отбора статей
Heart rate variability in acute myocardial infarction patients undergoing primary coronary angioplasty // The American Journal of Cardiology, 2000. Usefulness of fragmented QRS on a 12-lead electrocardiogram in acute coronary syndrome for predicting mortality // The American Journal of Cardiology, 2009 Prognostic significance of fragmented QRS complex for predicting the risk of recurrent cardiac events in patients with Q-Wave myocardial infarction // The American Journal of Cardiology, 2007.
АНАЛИЗ ЭПИДЕМИОЛОГИЧЕСКОЙ СИТУАЦИИ ПО ОСОБО ОПАСНЫМ ИНФЕКЦИЯМ И МИРОВОЙ ОПЫТ ИХ ПРОГНОЗИРОВАНИЯ
ANALYSIS OF THE EPIDEMIOLOGICAL SITUATION OF ESPECIALLY DANGEROUS INFECTIONS AND THE WORLD EXPERIENCE OF THEIR
In this regard, it is extremely important to study the development of the global epidemiological situation and predict particularly dangerous infections. Analysis of literature data on the epidemiological situation of particularly dangerous infections in the Republic of Kazakhstan and countries of the near and far abroad, as well as world experience in their prediction. The analysis of literature data showed that today the epidemiological situation for particularly dangerous infections is an urgent problem that is being studied at the global level.
АСА ҚАУІПТІ ИНФЕКЦИЯЛАР БОЙЫНША ЭПИДЕМИОЛОГИЯЛЫҚ ЖАҒДАЙДЫ ТАЛДАУ ЖӘНЕ ОЛАРДЫ БОЛЖАУДЫҢ ӘЛЕМДІК
GENETIC ASSOCIATIONS WITH RHEUMATOID ARTHRITIS SUSCEPTIBILITY. REVIEW
ГЕНЕТИЧЕСКИЕ АССОЦИАЦИИ С ПРЕДРАСПОЛОЖЕННОСТЬЮ К РЕВМАТОИДНОМУ АРТРИТУ. ОБЗОР ЛИТЕРАТУРЫ
Всего было найдено 206 ссылок, из которых 100 соответствовали критериям отбора и были включены в данный обзор.
РЕВМАТОИДТЫ АРТРИТКЕ БЕЙІМДІЛІГІ БАР ГЕНЕТИКАЛЫҚ АССОЦИАЦИЯЛАР. ӘДЕБИЕТТІК ШОЛУ
Immunobiological association of PTPN22 rs2476601 and STAT4 rs7574865 polymorphisms with rheumatoid arthritis: A meta-analysis update. Polymorphisms of E26-specific transformation-1 (ETS1) and WDFY family member 4 (WDFY4) in Chinese patients with rheumatoid arthritis // Int J Mol Sci. Association between CTLA-4 gene polymorphism and risk of rheumatoid arthritis: a meta-analysis // Aging (Albany NY).
ПРИНЦИПЫ ДИЕТОТЕРАПИИ В ПЛАНИРОВАНИИ ПИТАНИЯ ПРИ САХАРНОМ ДИАБЕТЕ 1 ТИПА У ДЕТЕЙ
PRINCIPLES OF DIET THERAPY IN FOOD PLANNING FOR TYPE 1 DIABETES MELLITUS IN CHILDREN
ТИПТІ ҚАНТ ДИАБЕТІНЕ АРНАЛҒАН ТАҒАМДЫ ЖОСПАРЛАУДА ДИЕТОТЕРАПИЯ ПРИНЦИПТЕРІ
- mail: [email protected] Телефон: 8 705 202 60 30
Principles of dietary therapy in food planning for type 1 diabetes mellitus in children // Nauka i Zdravookhranenie [Science & Healthcare]. Variables Associated with Severe Hypoglycemia in Children and Adolescents with Type 1 Diabetes: A Population Study // Published in February. The ongoing challenge of diabetic ketoacidosis in children and adolescents with type 1 diabetes // The Journal of Pediatrics May 2020.
СИНДРОМ ВЕСТА: ЭТИОЛОГИЯ И РАННИЕ ДИАГНОСТИЧЕСКИЕ ПРИЗНАКИ. ОБЗОР ЛИТЕРАТУРЫ
VESTA SYNDROME: ETIOLOGY AND EARLY DIAGNOSTIC SIGNS. LITERATURE REVIEW
West syndrome is a severe variant of epileptic diseases in children due to complex therapeutic tactics and impaired mental development. Objective: to analyze and systematize publications devoted to the study of the etiology and early diagnostic signs of West syndrome. West syndrome is characterized by a combination of cluster spasms, hypsarrhythmia on an electroencephalogram, and psychomotor regression.
ВЕСТ СИНДРОМЫ: ЭТИОЛОГИЯСЫ ЖӘНЕ ЕРТЕ ДИАГНОСТИКАЛЫҚ БЕЛГІЛЕРІ. ӘДЕБИЕТКЕ ШОЛУ
- mail: [email protected] Тел.: +7 (707) 799 88 30
Safety and efficacy of vigabatrin for the treatment of infantile spasms // Journal of Central Nervous System Disease. A proposal for case definitions and outcome measures in studies of infantile spasms and West syndrome: consensus statement from the West Delphi Group // Epilepsy. The response to ACTH is determined early in the treatment of infantile spasms // epileptic disorders.
A MODERN VIEW ON THE ETHIOPATOGENESIS OF PRETERN BIRTH. REVIEW
СОВРЕМЕННЫЙ ВЗГЛЯД НА ЭТИОПАТОГЕНЕЗ ПРЕЖДЕВРЕМЕННЫХ РОДОВ. ОБЗОР ЛИТЕРАТУРЫ
МЕРЗІМІНЕН БҰРЫН БОСАНУДЫҢ ЭТИОПАТОГЕНЕЗIНЕ ЗАМАНАУИ КӨЗҚАРАС. ӘДЕБИЕТТIК ШОЛУ
- The central nervous system
- Complications leading to preterm birth
- An infectious factor
- Immunological and molecular genetic aspects of the pathogenesis of spontaneous preterm birth
Objective: An analysis of the literature on the role of etiopathogenetic mechanisms of preterm birth. The study of the immunological factor in the development of preterm labor has a long history. A brief mention of the role of toll-like receptors in the pathogenesis of preterm labor was made above.
ФАКТОРЫ РИСКА КОГНИТИВНЫХ НАРУШЕНИЙ, ГЕНДЕРНЫЕ ОСОБЕННОСТИ. ОБЗОР ЛИТЕРАТУРЫ
RISK FACTORS FOR COGNITIVE IMPAIRMENT, GENDER CHARACTERISTICS. LITERARY REVIEW
Women have a higher risk of developing Alzheimer's-related dementia, and men have a higher risk of developing vascular dementia.
ТАНЫМДЫҚ БҰЗЫЛУЛАРДЫҢ ҚАУІП ФАКТОРЛАРЫ, ГЕНДЕРЛІК ЕРЕКШЕЛІКТЕРІ. ӘДЕБИЕТКЕ ШОЛУ
Факторы, ассоциируемые со снижением когнитивных функций. [24]
- mail: [email protected] Телефон: + 77779809317
Risk profiles for mild cognitive impairment and progression to dementia are gender specific // J Neurol Neurosurg Psychiatry. Increased risk of cognitive impairment or dementia in women who have undergone oophorectomy before menopause // Neurology. Risk profiles for mild cognitive impairment vary by age and sex: the Sydney Memory and Aging Study // Am J Geriat Psychiat.
OVERVIEW OF RISKS AFFECTING OF QUALITY OF MEDICAL SERVICES IN THE EXISTING QUALITY MANAGEMENT SYSTEM
IN MEDICAL ORGANIZATIONS AT THE PRESENT STAGE
ОБЗОР РИСКОВ, ВЛИЯЮЩИХ НА КАЧЕСТВО МЕДИЦИНСКИХ УСЛУГ В СУЩЕСТВУЮЩЕЙ СИСТЕМЕ УПРАВЛЕНИЯ КАЧЕСТВОМ
ҚАЗІРГІ КЕЗЕҢДЕ МЕДИЦИНАЛЫҚ ҰЙЫМДАРДАҒЫ ҚОЛДАНЫСТАҒЫ САПА МЕНЕДЖМЕНТІ ЖҮЙЕСІНДЕ МЕДИЦИНАЛЫҚ ҚЫЗМЕТ
САПАСЫНА ӘСЕР ЕТЕТІН ТӘУЕКЕЛДЕРДІ ҚАРАСТЫРУ
Study selection for review
Operational: Risks affecting the MO's core business in the execution of its strategy. Regular monitoring of evidence-based medical achievements to determine the likelihood of success in the application of medical technologies. Analysis of the use of resources (specialized specialists, equipment) in the provision of medical services with determination of the time spent.
КАТЕХОЛАМИНЫ И ИХ МЕТАБОЛИТЫ В РЕГУЛЯЦИИ
АКТИВНОСТИ МИТОХОНДРИАЛЬНЫХ И ЦИТОПЛАЗМАТИЧЕСКИХ ФЕРМЕНТОВ СЕРДЦА. ОБЗОР ЛИТЕРАТУРЫ
CATECHOLAMINES AND THEIR METABOLITES IN REGULATION OF ACTIVITY OF MITOCHONDRIAL AND CYTOPLASMIC HEART ENZYMS
LITERATURE REVIEW
Search strategy: Research papers were searched in the search engines Scopus, Web of Science Core Collection, MedLine, PubMed, Cochrane Library, Google Scholar, in the electronic scientific library e-Library.ru, CyberLeninka. Results and conclusions: An analysis of the literature data showed that hormone mediators of the sympathio-adrenal system, by changing the activity of the enzymes of the respiratory chain of cardiomyocyte mitochondria, regulate the processes of tissue respiration. In cardiomyocytes, adrenaline, by activating the cytosolic enzymes of the metabolism of purine nucleotides AD and AMPD, which increases the level of lipid peroxidation (MDA and DC), increases the activity of the antioxidant defense enzymes GPO and catalase, indicating that adrenaline, by adrenoceptor mechanisms, lead the body to a state of oxidative stress.
ЖҮРЕКТІҢ МИТОХОНДРИЯЛЫҚ ЖӘНЕ ЦИТОПЛАЗМАЛЫҚ ФЕРМЕНТТЕРДІҢ БЕЛСЕНДІЛІГІН РЕТТЕУДЕГІ КАТЕХОЛАМИНДЕР
Стратегия поиска: поиск научных статей осуществлялся в поисковых системах Scopus, Web of Science Core Collection, MedLine, PubMed, Cochrane Library, Google Scholar, в электронной научной библиотеке e-Library.ru, КиберЛенинка. Исследование [29] влияния продуктов окисления катехоламинов на митохондриальную сукцинатдегидрогеназу показало, что адреноксил (адренохроммоносемикарбозон) в дозе 0,2 мг/100 г, введенный за 30 мин до исследования, как и дофамин и норадреналин, активировал СДГ в сердце и снижение активности в печени, головном мозге и почках. Как показали наши исследования влияния катехоламинов на Mg-активированную, ДНФ-стимулированную АТФазу (Mg-АТФ-азу) митохондрий, дофамин и норадреналин, введенные животным за 15 минут до исследования, снижают активность Mg-АТФазы. в митохондриях, сердце, печени, мозге и почках.
